PERISCOPE

The PERISCOPE study will involve 394 people with inflammatory arthritis on biologics from NHS hospitals across the UK who require orthopaedic surgery. Participants will be randomly allocated to either stopping or continuing their biologics before undergoing orthopaedic surgery. We will conduct regular patient assessments for the first 12 weeks following surgery. This will give a complete picture during the recovery period after the operation. We are using PROMIS-29; a quality of life questionnaire as the main study outcome. We will also ask patients about their health and wellbeing periodically over the next 12 months. We will record complications (infections, flares), disease activity, medications, how often people seek care and who with. We will compare costs and interview participants and clinicians to understand their views and experiences.

See this video for more information: https://www.youtube.com/watch?v=CSTsYUmSHCU&t=30s